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Does doxylamine succinate make you sleepy? Drowsiness is one of the major side effects of some antihistamines, such as diphenhydramine (Benadryl) and doxylamine succinate (the antihistamine found in Nyquil). And because of their powerful sedating qualities, antihistamines are also the active ingredients found in numerous over-the-counter sleep aids.
Are Benadryl and Unisom the same thing? Most are simply antihistamines in sheep's clothing. (Yes, that's a joke.) The majority of them — ZzzQuil, TylenolPM and Unisom SleepGels — contain diphenhydramine as the active ingredient, the same compound in Benadryl. (Unisom SleepTabs use doxylamine, another antihistamine.)
Is doxylamine succinate bad for your liver? No evidence of enzyme induction has been found in humans. Doxylamine succinate causes liver damage in mice; this effect may be related to its hepatocarcinogenicity. Doxylamine succinate is considered not to be genotoxic.
What are the side effects of taking doxylamine succinate? Although you likely wouldn't experience most side effects, and may not have any at all, some that occur commonly with doxylamine include: Drowsiness. Dizziness. Loss of coordination. Headache. Stomach pain. Thick lung secretions. Dry mouth or nose. Hyperactivity.
Can I take doxylamine succinate and diphenhydramine together? Using dextromethorphan together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating.
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